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Jmir Medical Informatics

July 21, 2026

An AI-Based System for Enhancing Communication with Patients Prior to Surgery: A Comprehensive Clinical Assessment

Motoki Sato
Sou Nagata
Mizuho Ohnuma
Hidekazu Takahashi
Tomoaki Kakazu
Masayuki Yamamura
Atsushi Yoshikawa
Yuki Matsushita
July 21, 2026

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Quiz

Objective: To assess the potential of AI-based systems, particularly large language models (LLMs), in improving communication with patients before surgical proc

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3 min

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Frontiers In Neurology

July 20, 2026

Oromandibular Dystonia Resistant to Botulinum Toxin: Two Case Studies Highlighting Condylar Dislocation as a Structural Mimicker

Olcay Şakar
Berk Bilgen
Bora Edim Akalın
Kazuya Yoshida
July 20, 2026

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Objective: To illustrate cases of oromandibular dystonia (OMD) misdiagnosed due to long-standing condylar dislocation and to highlight the need for diagnostic r

...more

3 min

Botulinum toxin therapy is a standard treatment for oromandibular dystonia (OMD), but lack of response may indicate a need for reevaluation.
Long-standing condylar dislocation can mimic OMD symptoms, including mandibular deviation and impaired closure, complicating diagnosis.
Two cases demonstrated that patients initially diagnosed with OMD improved after structural correction for long-standing condylar dislocation.
Botulinum toxin non-response should prompt clinicians to consider structural disorders like condylar dislocation before continuing treatment.
A thorough dental and oral/maxillofacial evaluation is recommended for patients with OMD-like symptoms and persistent occlusal disturbances.

...more

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Frontiers In Surgery

July 17, 2026

Case Study: Concurrent Occurrence of Lingual Osseous Choristoma and Suprahyoid Thyroglossal Duct Cyst: Understanding the Embryological Connection of the Thyroglossal-Hyoid Axis

Hyun Je Kim
Sun-Young Jun
Ho-Kyung Lim
July 17, 2026

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Objective: To report a rare case of concurrent lingual osseous choristoma and suprahyoid thyroglossal duct cyst and explore their potential embryological connec

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3 min

Lingual osseous choristoma is a rare benign lesion characterized by mature bone tissue in the tongue's soft tissue.
Thyroglossal duct cysts are common congenital lesions resulting from incomplete involution of the thyroglossal duct.
A 26-year-old woman presented with a posterior tongue mass and a suprahyoid thyroglossal duct cyst, both rarely occurring together.
Surgical excision confirmed the diagnoses of lingual osseous choristoma and thyroglossal duct cyst, with no complications at 18 months.
The case suggests a potential embryological link between lingual osseous lesions and the thyroglossal duct system.

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Frontiers In Immunology

July 17, 2026

Extract of Melissa officinalis selectively inhibits STAT1 signaling pathways in oral epithelial cells

Issam Rasheed
Layla Panahipour
Ronald A. Glabonjat
Reinhard Gruber
July 17, 2026

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Objective: To investigate the effects of Melissa officinalis extract (MOE) on inflammatory signaling in oral epithelial cells, particularly its modulation of JA

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3 min

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Frontiers In Surgery

July 16, 2026

Evaluation of the Consistency of the Frankfort Horizontal Plane Using 3D Reconstruction from CBCT and Comparison with Lateral Cephalometric Radiographs

Zhiwen Li
Liuli Jin
Xueyang Zhang
Pan Jiang
Yuan Lin
Qun Yang
July 16, 2026

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Objective: To investigate the reproducibility of the Frankfort horizontal plane (FHP) established using CBCT-based three-dimensional reconstruction and to evalu

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3 min

The study evaluated the reproducibility of the Frankfort horizontal plane (FHP) using CBCT-based 3D reconstruction in patients with facial deformities.
Twenty-seven patients underwent both CBCT scanning and lateral cephalometric radiography for comparison of FHP establishment methods.
CBCT 3D reconstruction demonstrated good reproducibility for FHP, while lateral cephalometric measurements showed larger reproducibility errors.
Intra-class correlation coefficients and Bland–Altman analysis were used to assess reproducibility and agreement between the two methods.
The findings suggest that CBCT-based methods may enhance the reliability of FHP construction for craniofacial diagnosis and treatment planning.

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Frontiers In Endocrinology

July 15, 2026

Diabetic Ketoacidosis and Reversible Sepsis-Induced Cardiomyopathy Triggered by a Periapical Abscess: A Case Study

Jixia Jin
Lian Liao
Yinhang Ren
Guiyun Li
Yuyang Qiu
July 15, 2026

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Objective: To present a case of diabetic ketoacidosis (DKA) and sepsis-induced cardiomyopathy (SICM) triggered by a periapical abscess in a patient with poorly

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3 min

Diabetic ketoacidosis (DKA) is a severe complication of diabetes, often triggered by infections, particularly in patients with poor glycemic control.
Odontogenic infections, such as periapical abscesses, can lead to life-threatening DKA and septic shock in diabetic patients.
A 57-year-old female with poorly controlled type 2 diabetes presented with severe DKA and sepsis due to a left submandibular abscess.
Echocardiography revealed severe left ventricular systolic dysfunction, consistent with sepsis-induced cardiomyopathy, which improved after treatment.
Multidisciplinary management, including antibiotics and fluid resuscitation, led to rapid clinical improvement and complete recovery of cardiac function.

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Frontiers In Pain Research

July 14, 2026

Comparative Analysis of Efficacy and Safety of Acupuncture Techniques for Primary Trigeminal Neuralgia: A Systematic Review and Network Meta-Analysis

Guanxi Ren
Yinsu Chen
Xinyu Zhang
Yaqing Guo
Weijia Peng
Kunping Jia
Jiawen Li
Yulong Shan
Xinyue Qiu
Guofeng Cai
July 14, 2026

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Objective: To compare the efficacy and safety of various acupuncture therapies for PTN using a network meta-analysis (NMA). Approach: Methods: Randomized contro

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3 min

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Frontiers In Oncology

July 10, 2026

Evaluating Normal Tissue Complication Probability Models for Osteoradionecrosis of the Jaw: A Comprehensive Review and Framework for Clinical Application Beyond Dose-Volume Histograms

Jaymit Patel
July 10, 2026

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Objective: To review the current evidence base for NTCP models related to osteoradionecrosis (ORN) in head and neck cancer and propose a framework for clinical

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3 min

Head and neck cancer has a global burden of approximately 880,000 new cases annually, with radiotherapy used in about 75% of treatments.
Osteoradionecrosis (ORN) occurs in 7-10% of patients and is characterized by severe complications affecting quality of life.
The NTCP model developed by van Dijk et al. identified D30% and pre-RT dental extraction as key predictors of ORN.
The WAFT model introduced a time-to-event framework, showing that each additional Gray of radiation shortens the time to ORN onset.
Methodological limitations in existing NTCP models include insufficient cohort diversity and inadequate characterization of RT protocols.

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Frontiers In Medicine

July 10, 2026

Models for Predicting Oral Frailty in Elderly Populations: A Comprehensive Scoping Review

Yongjun Chen
Huixian Tang
Bo Li
Liping Yuan
July 10, 2026

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Quiz
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Objective: To systematically map existing oral frailty risk prediction models for older adults, focusing on model development methods, outcome definitions, reta

...more

3 min

Oral frailty is linked to systemic functional decline and adverse outcomes in older adults, necessitating accurate risk identification.
Seventeen studies were included in the review, primarily cross-sectional and concentrated in China, with varied definitions of oral frailty.
Logistic regression was commonly used for model development, while nomograms were typically employed to present prediction tools.
Fifteen studies reported internal validation, but only two provided external validation, indicating a high risk of bias across all studies.
Future research should focus on prospective multicenter designs, standardized outcome definitions, and external validation for improved applicability.

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Frontiers In Psychiatry

July 9, 2026

Correction: Oral Discomfort and Health Behaviors in Patients Treated with Typical versus Atypical Antipsychotics

Jukka H. Meurman
Heikki Murtomaa
Marja Koski
July 9, 2026

Summary
Takeaways
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Poll

Objective: To correct authorship and citation details in the published article regarding oral discomfort and health behaviors in patients treated with antipsych

...more

Marja Koski was omitted as an author in the original article due to a misunderstanding regarding her status.
The corrected author list now includes Jukka H. Meurman, Heikki Murtomaa, and Marja Koski.
The article's citation has been updated to reflect the inclusion of Marja Koski as an author.
The copyright statement has been revised to acknowledge the contributions of all authors under the Creative Commons Attribution License.
The In Memoriam statement has been corrected to honor the late psychiatrist Heikki Rantanen and dentist Kaija Koski.

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Conexiant

July 8, 2026

Former Dentist Ordered to Pay for Unlawful Prescribing

Kathryn Wighton
July 8, 2026
2 min

Summary
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Quiz

Objective: To report on the legal consequences faced by William C. Gardner, DDS, for unlawfully issuing controlled-substance prescriptions. Approach: Legal Acti

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1 min

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Conexiant

July 7, 2026

Medical Oddities: When a Brush Beats a Scalpel

Teraya Smith
July 7, 2026
5 min

Summary
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Quiz

Objective: To evaluate the effectiveness of a rapid 4-gene mRNA test, qMIDSV3, as a triage tool for distinguishing oral squamous cell carcinoma from low-risk or

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1 min

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Frontiers In Pain Research

July 7, 2026

Developmental Patterns of Pain Intensity and Contributing Factors in Pediatric Recurrent Aphthous Stomatitis: An Analysis Using Latent Variable Growth Mixture Modeling

Hu Ruping
Song Hongjie
July 7, 2026

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Objective: To explore the potential categories of pain intensity development trajectory in children with recurrent aphthous stomatitis and analyze the influenci

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3 min

The study analyzed pain intensity trajectories in 200 children with recurrent aphthous stomatitis over a 14-day period.
Three pain intensity categories were identified: high pain relief type, moderate pain improvement type, and low pain stable type.
Independent factors influencing pain trajectories included ulcer size, number of ulcers, ulcer type, frequency of attacks, and picky eating.
Univariate and multivariate logistic regression analyses were used to assess the impact of these factors on pain trajectory differences.
The findings aim to aid in identifying children at high risk for severe pain trajectories and improving pain management strategies.

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Frontiers In Pediatrics

July 7, 2026

Impact of Early Myofunctional Therapy on Maxillary Arch Growth in Children Aged 4 to 7 with Mild Oral Habits: A Controlled Pilot Investigation

Qiwen Xiao
Junqing Ma
July 7, 2026

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Objective: To determine the effects of organized early myofunctional training on the development of the maxillary arch in children aged 4–7 with mild oral habit

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The study involved 64 children aged 4 to 7, divided into intervention and control groups to assess myofunctional therapy's impact on maxillary arch growth.
The intervention group received 12 months of myofunctional training and habit cessation counselling, while the control group received counselling only.
Significant increases in intercanine width, intermolar width, and arch perimeter were observed in the intervention group compared to controls after 12 months.
Habit cessation rates were higher in the intervention group, with 87.5% achieving cessation compared to 65.6% in the control group.
Orofacial muscle function scores improved significantly more in the intervention group, indicating the potential benefits of early myofunctional therapy.

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Jama Network Open

July 7, 2026

Opioid Administration and Pain Management Outcomes in Opioid-Naive Individuals with Acute Pain

Molly Moore Jeffery
Fernanda Bellolio
Nancy Chang
Summer Allen
Marie-Carmelle Elie-Turenne
W. Jonathan Fillmore
Gregg H. Gilbert
Rebekah Heckmann
Patricia Koussis
Christine Lee
Heather Lipkind
Tamra E. Meyer
Teryl K. Nuckols
Jessica D. Ritchie
Michael A. Pacanowski
David B. Page
Mat Soukup
Stephen Tamang
Sam Torbati
Doug Wallace
Lauren Walter
Yueqin Zhao
Nilay D. Shah
Mitra Ahadpour
Joseph S. Ross
July 7, 2026

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Objective: To collect patterns of treatment use and pain trajectories among opioid-naive patients prescribed opioids for acute pain across various clinical sett

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3 min

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Frontiers In Surgery

July 6, 2026

Advancements in AI for Perioperative Risk Assessment and Complication Management in Craniomaxillofacial Surgery: Current Insights and Future Perspectives

HaiLian Chen
Shuang Zou
Linlin Zheng
July 6, 2026

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Objective: To summarize recent advances in AI applications for perioperative risk stratification and complication management in craniomaxillofacial surgery. App

...more

3 min

Craniomaxillofacial surgery involves complex anatomy and high surgical risks, necessitating improved perioperative management strategies.
Artificial intelligence offers potential advancements in perioperative risk assessment and complication management in craniomaxillofacial surgery.
AI applications in this field include preoperative risk assessment, intraoperative decision support, and postoperative outcome quantification.
Current challenges in AI implementation include data quality, model interpretability, and the need for clinical integration.
Future directions for AI in perioperative care focus on multimodal, explainable, and generative AI for personalized management systems.

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Arthritis Care & Research

July 6, 2026

Exploring the Impact of Orofacial Symptoms and Treatment Preferences Among Systemic Sclerosis Patients: Findings from a Comprehensive Global Survey

Eleni Deligianni
Lee Shapiro
Deana Gibbs
Zsuzsanna H. McMahan
Michael Hughes
July 6, 2026

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Objective: To define the burden, unmet needs, and treatment preferences associated with orofacial involvement in systemic sclerosis (SSc) to inform patient-driv

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3 min

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Frontiers In Surgery

July 2, 2026

Innovative Surgery-First Segmental Orthognathic Technique for Managing Hemimandibular Elongation: A Modified Approach

Jiawen Si
Yilang Du
Jingyang Huang
Hongbo Yu
Guofang Shen
July 2, 2026

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Objective: To introduce a pilot study of a modified surgery-first segmental orthognathic surgery technique for managing hemimandibular elongation (HE) and evalu

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