Comparative Evaluation of Growth Factor Bioavailability–Enhanced Allograft Vs Autogenous Bone Graft in Anterior Maxillary Ridge Augmentation - Report - DentalSpire

Comparative Evaluation of Growth Factor Bioavailability–Enhanced Allograft Vs Autogenous Bone Graft in Anterior Maxillary Ridge Augmentation

  • By

  • Ren Chang, DDS

  • July 1, 2026

  • 10 min

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Clinical Report: Comparative Evaluation of Growth Factor Bioavailability–Enhanced Allograft

Overview

This case report evaluates the effectiveness of a growth factor bioavailability–enhanced allograft (GFBA) in anterior maxillary ridge augmentation. Both grafting methods resulted in successful ridge augmentation and stable implant placement after 11 months.

Background

Alveolar ridge deficiencies can hinder implant placement, particularly in the anterior maxilla. Autogenous bone grafting is the standard treatment but carries risks of donor site morbidity. The introduction of GFBA aims to provide a viable alternative with enhanced biological signaling for bone regeneration.

Data Highlights

Both GFBA and autogenous grafts demonstrated successful ridge augmentation at 11 months, with stable peri-implant bone levels confirmed by follow-up radiographs.

Key Findings

  • GFBA showed a homogeneous trabecular pattern and advanced integration at the augmentation site.
  • Autogenous graft demonstrated ongoing remodeling and integration.
  • Implants were successfully placed at both grafted sites.
  • Significant dimensional changes can occur post-extraction, necessitating ridge augmentation.

Clinical Implications

Understanding the biological properties of graft materials can aid in selecting appropriate treatment options for alveolar ridge augmentation.

Conclusion

Both methods achieved successful outcomes in this case report.

Related Resources & Content

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  4. Comparative Effectiveness of Cancellous Allogenic and Autologous Bone Grafting in Tunnel Filling During Two-Stage Revision ACL Surgery, Springer, 2020
  5. Horizontal Ridge Augmentation in the Anterior Maxilla - Consensus Statements - Home - ITI, ITI, 2023
  6. Horizontal ridge augmentation through ridge expansion via osseodensification, guided bone regeneration and ridge‑split: Systematic review and meta‑analysis of clinical trials, PMC, 2023
  7. Development of a growth factor bioavailability enhanced allograft (GFBA) for bone regeneration, Cell and Tissue Banking, Springer Nature, 2025
  8. Horizontal Ridge Augmentation in the Anterior Maxilla - Consensus Statements - Home - ITI
  9. Horizontal ridge augmentation through ridge expansion via osseodensification, guided bone regeneration and ridge‑split: Systematic review and meta‑analysis of clinical trials - PMC
  10. Development of a growth factor bioavailability enhanced allograft (GFBA) for bone regeneration | Cell and Tissue Banking | Springer Nature Link

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