Clinical outcomes of vital pulp therapy versus root canal treatment in immature permanent teeth with pulpal involvement: a meta-analysis - Scorecard - DentalSpire

Clinical outcomes of vital pulp therapy versus root canal treatment in immature permanent teeth with pulpal involvement: a meta-analysis

  • By

  • Siji Gu

  • Yuyun Yang

  • May 20, 2026

  • 0 min

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Clinical Scorecard: Comparative Analysis of Clinical Outcomes between Vital Pulp Therapy and Root Canal Treatment in Immature Permanent Teeth with Pulpal Involvement: A Meta-Analysis

At a Glance

CategoryDetail
Condition
Key MechanismsVital pulp therapy (VPT) preserves pulp vitality, which is crucial for apexogenesis and structural development, leading to improved clinical outcomes.
Target Population
Care Setting

Key Highlights

  • VPT shows significantly higher odds of success compared to RCT (OR = 1.37, p < 0.05).
  • Marked benefit of VPT in immature teeth (OR = 3.01, p < 0.01).
  • Complete/coronal pulpotomy yields better outcomes (OR = 2.47, p < 0.05).
  • Bioceramic-based VPT achieves near-complete success in randomized trials (98/98 teeth).
  • Longer follow-up (≥24 months) correlates with improved outcomes (OR = 2.03, p < 0.01).

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Follow-up assessments should be conducted at intervals of 6, 12, and 24 months post-treatment, with specific criteria for clinical and radiographic evaluation.

      Risks

        Patient & Prescribing Data

        Immature permanent teeth in children and adolescents with pulpal involvement.

        VPT may offer a biologically conservative alternative to RCT, promoting pulp vitality and tooth development.

        Clinical Best Practices

        • Utilize bioceramic materials for VPT to enhance healing, supported by recent studies.
        • Select appropriate VPT modality based on the extent of pulpal involvement, considering clinical evidence.
        • Educate patients and guardians on the benefits of preserving pulp vitality, referencing successful case studies.

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