Risk prediction models for oral frailty in older adults: a scoping review
By
Yongjun Chen
Huixian Tang
Bo Li
Liping Yuan
July 10, 2026
Clinical Scorecard: Models for Predicting Oral Frailty in Elderly Populations: A Comprehensive Scoping Review
At a Glance
Category Detail
Condition Oral Frailty
Key Mechanisms Age-related decline in oral function associated with systemic functional decline.
Target Population Older adults aged 60 years or older.
Care Setting Community, hospital, rural, and disease-specific settings.
Key Highlights
Seventeen studies included, mostly cross-sectional and geographically concentrated in China. Reported proportion of oral frailty ranged from 25.50% to 92.50%. Logistic regression was commonly used for model development; nomograms for display. High overall risk of bias in all studies; limited external validation. Area under the receiver operating characteristic curve ranged from 0.725 to 0.985.
Guideline-Based Recommendations
Diagnosis
Oral frailty should be defined and assessed according to specific criteria in each study.
Management
Healthcare professionals should use prediction models to identify high-risk individuals for targeted interventions.
Monitoring & Follow-up
Future studies should standardize outcome definitions and reporting for better applicability.
Risks
High risk of bias and limited generalizability of existing models.
Patient & Prescribing Data
Older adults at risk of oral frailty.
Models may assist in timely screening and risk stratification.
Clinical Best Practices
Adopt prospective multicenter designs for future studies. Perform external validation of prediction models before routine implementation.
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