Toothpastes may transiently alter salivary calcium
Three fluoride formulations produced distinct calcium patterns immediately after brushing, but differences disappeared within 60 minutes.
By
Andrea Surnit
October 5, 2026
Clinical Scorecard: Toothpastes may transiently alter salivary calcium
At a Glance
Category Detail
Condition Salivary calcium concentration changes
Key Mechanisms Different fluoride toothpaste formulations affect salivary calcium levels post-brushing.
Target Population Healthy young adults
Care Setting Clinical trial
Key Highlights
Three fluoride toothpaste formulations were tested: Dentalux, Parodontax, and Sensodyne. Significant differences in salivary calcium levels were observed immediately after brushing. By 60 minutes, no statistically significant differences remained among the toothpaste formulations. The study involved 48 participants with a mean age of 22.55 years.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Healthy young adults
Different toothpaste formulations produce varying short-term effects on salivary calcium.
Clinical Best Practices
Related Resources & Content