To evaluate the association between periodontal health interventions and the risk of first-ever ischemic stroke.
Key Findings:
Periodontal interventions were associated with a lower likelihood of ischemic stroke.
Tooth scaling showed the greatest protective effect against ischemic stroke.
Regular dental care was linked to reduced stroke risk compared to episodic or no care.
Higher toothbrushing frequency correlated with lower stroke risk.
Intensive periodontal treatments had mixed results, with some increasing stroke risk in younger patients, particularly tooth extraction.
Interpretation:
The findings suggest that maintaining good periodontal health, particularly through tooth scaling, may lower the risk of ischemic stroke, although results vary by age and population.
Limitations:
All included studies were observational, limiting causal inference due to potential confounding factors.
Inconsistent adjustment for confounders like smoking.
Most data derived from Asian populations, affecting generalizability.
Substantial heterogeneity in study designs and definitions of interventions.
Conclusion:
Periodontal health interventions, especially tooth scaling, may reduce the risk of ischemic stroke, but further research is needed to clarify findings across different populations and age groups.
