Objective:

To assess the 6-month effects of Kangfuxin solution on peri-implant health and masticatory function in chronic periodontitis patients undergoing implant rehabilitation, specifically evaluating its efficacy as an adjunctive therapy.

Approach:

Key Findings:

• Mean PD decreased from 4.8 ± 0.6 mm to 3.4 ± 0.5 mm (p < 0.001).
• Mean CAL decreased from 5.1 ± 0.8 mm to 4.0 ± 0.7 mm (p < 0.001).
• Peri-implantitis incidence was 3.0%, significantly lower than the historical benchmark of 12% (p = 0.001).
• Bite force improved by 39.6% (p < 0.001).
• IL-1β, IL-6, and TNF-α levels decreased significantly (all p < 0.001).
• Adverse events were minimal (1.3% mild mucosal irritation); implant survival was 99.6%.

Interpretation:

Adjunctive Kangfuxin solution significantly improved peri-implant health and masticatory function, indicating its potential as a beneficial adjunct in implant rehabilitation for chronic periodontitis patients.

Limitations:

• Retrospective design without a concurrent control group, which may introduce biases.
• Limited generalizability due to single-center study.

Conclusion:

Kangfuxin solution shows promise in enhancing peri-implant parameters and masticatory function, warranting further randomized trials to confirm its efficacy in high-risk implant patients and explore long-term effects.

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