Oromandibular dystonia unresponsive to botulinum toxin: two illustrative cases of condylar dislocation as a structural mimic - Summary - DentalSpire

Oromandibular Dystonia Resistant to Botulinum Toxin: Two Case Studies Highlighting Condylar Dislocation as a Structural Mimicker

  • By

  • Olcay Şakar

  • Berk Bilgen

  • Bora Edim Akalın

  • Kazuya Yoshida

  • July 20, 2026

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Objective:

To illustrate cases of oromandibular dystonia (OMD) misdiagnosed due to long-standing condylar dislocation and to highlight the need for diagnostic reassessment in such cases.

Approach:
  • Case Presentation: Two patients initially diagnosed with OMD underwent botulinum toxin injections without benefit, later found to have long-standing condylar dislocation.
  • Diagnostic Evaluation: Both cases involved comprehensive dental and oral/maxillofacial evaluations, including panoramic radiography.
Key Findings:
  • Both patients showed no improvement from botulinum toxin injections.
  • Panoramic radiography revealed long-standing condylar dislocation as the primary diagnosis.
  • Patients improved after structural correction and prosthetic rehabilitation.
Interpretation:

Botulinum toxin non-response should prompt a systematic reassessment for structural disorders in patients with suspected OMD.

Limitations:
  • The cases do not represent the frequency or full clinical spectrum of structural mimics among patients with suspected OMD, and selection bias may affect the generalizability of the findings.
Conclusion:

The findings highlight the importance of considering structural disorders in patients with OMD-like symptoms who do not respond to botulinum toxin therapy.

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