Clinical outcomes of vital pulp therapy versus root canal treatment in immature permanent teeth with pulpal involvement: a meta-analysis - Takeaways - DentalSpire

Clinical outcomes of vital pulp therapy versus root canal treatment in immature permanent teeth with pulpal involvement: a meta-analysis

  • By

  • Siji Gu

  • Yuyun Yang

  • May 20, 2026

  • 0 min

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  • 1

    Vital pulp therapy (VPT) shows significantly higher success rates than root canal treatment (RCT) in immature permanent teeth with pulpal involvement.

  • 2

    Subgroup analyses indicate that VPT is particularly beneficial for immature teeth, complete pulpotomy, and follow-ups of 24 months or longer.

  • 3

    Bioceramic-based VPT achieved near-complete success in trials, while RCT outcomes plateaued at 79%-98% success rates.

  • 4

    Meta-regression identified tooth immaturity, full pulpotomy, and longer follow-up as positive prognostic factors for treatment success.

  • 5

    Despite favorable outcomes for VPT, the evidence remains insufficient for definitive conclusions, highlighting the need for larger studies.

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