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1
Vital pulp therapy (VPT) shows significantly higher success rates than root canal treatment (RCT) in immature permanent teeth with pulpal involvement.
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2
Subgroup analyses indicate that VPT is particularly beneficial for immature teeth, complete pulpotomy, and follow-ups of 24 months or longer.
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3
Bioceramic-based VPT achieved near-complete success in trials, while RCT outcomes plateaued at 79%-98% success rates.
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4
Meta-regression identified tooth immaturity, full pulpotomy, and longer follow-up as positive prognostic factors for treatment success.
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5
Despite favorable outcomes for VPT, the evidence remains insufficient for definitive conclusions, highlighting the need for larger studies.