Pain severity trajectory and influencing factors in children with recurrent aphthous stomatitis: a latent variable growth mixture model - Takeaways - DentalSpire

Pain severity trajectory and influencing factors in children with recurrent aphthous stomatitis: a latent variable growth mixture model

  • By

  • Hu Ruping

  • Song Hongjie

  • July 7, 2026

  • 0 min

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  • 1

    The study analyzed pain intensity trajectories in 200 children with recurrent aphthous stomatitis over a 14-day period.

  • 2

    Three pain intensity categories were identified: high pain relief type, moderate pain improvement type, and low pain stable type.

  • 3

    Independent factors influencing pain trajectories included ulcer size, number of ulcers, ulcer type, frequency of attacks, and picky eating.

  • 4

    Univariate and multivariate logistic regression analyses were used to assess the impact of these factors on pain trajectory differences.

  • 5

    The findings aim to aid in identifying children at high risk for severe pain trajectories and improving pain management strategies.

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