Harnessing Advanced Biologics to Enhance Bone Regeneration and Implant Success
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By
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George A. Mandelaris
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September 1, 2026
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3 min
5 Topic Commentaries
Harnessing Advanced Biologics to Enhance Bone Regeneration and Implant Success
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Alireza Moshaverinia, DDS, MS, PhD, FACP
Assistant Professor of Prosthodontics
•UCLA School of Dentistry
[Source]The light treatment helped harden the hydrogel, providing a more stable vehicle for delivery of the stem cells.
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Min Lee, PhD
Professor of Biomaterials Science
•UCLA School of Dentistry
[Source]This research will help us develop the next generation of hydrogel systems with high porosity and could greatly improve current bone graft materials.
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William V. Giannobile, DDS, MS, DMSc
Professor of Dentistry and Bioengineering; Director, Clinical Research Center
•University of Michigan
[Source]The FDA had approved our platelet-derived growth factor, but the delivery system was just a ceramic matrix with growth factor attached—essentially a dose-dumping system.
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Shuying (Sheri) Yang, MD, MS, PhD
Professor, Department of Basic & Translational Sciences
•University of Pennsylvania, Penn Dental Medicine
[Source]So we’re trying to think about how we can optimize the conditions, using a growth factor-infused scaffold so the growth factor is slowly released.
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Paula T. Hammond, PhD
David H. Koch Professor in Engineering; Department of Chemical Engineering
•Massachusetts Institute of Technology
[Source]This would allow the implant to last much longer, to its natural lifetime, with lower risk of failure or infection.
Based on findings from:
Harnessing Advanced Biologics to Enhance Bone Regeneration and Implant Success
George A. Mandelaris. Compendium, 2026.
https://compendiumlive.com/2026/09/harnessing/
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