DENTALE: a validated Dentofacial EvaluatioN Tool to standardize radiological Assessment of Late dental and maxillofacial adverse Effects following treatment for pediatric rhabdomyosarcoma - Scorecard - DentalSpire

DENTALE: a validated Dentofacial EvaluatioN Tool to standardize radiological Assessment of Late dental and maxillofacial adverse Effects following treatment for pediatric rhabdomyosarcoma

  • By

  • Koen B. Krommenhoek

  • Reinier C. Hoogeveen

  • E. Foster-Thomas

  • Willem M. M. Fennis

  • Frédérique J. M. San Giorgi

  • Matthew Krasin

  • Mark N. Gaze

  • Olga Slater

  • Gillian A. Whitfield

  • Daniel J. Indelicato

  • Henry C. Mandeville

  • Shermaine Pan

  • Marianne C. Aznar

  • Johannes H. M. Merks

  • Alfred G. Becking

  • Marinka L. F. Hol

  • May 22, 2026

  • 0 min

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Clinical Scorecard: DENTALE: A Validated Tool for Standardizing Radiological Evaluation of Late Dental and Maxillofacial Adverse Effects in Pediatric Rhabdomyosarcoma Survivors

At a Glance

CategoryDetail
Condition
Key MechanismsRadiographic evaluation of dental and maxillofacial structures affected by cancer treatments (source needed).
Target Population
Care Setting

Key Highlights

  • DENTALE tool developed for assessing late dental effects on OPGs (source needed).
  • Interobserver reliability demonstrated ICC of 0.857–0.939 (source needed).
  • Achieved 100% sensitivity and 90% specificity for referral decisions (source needed).
  • Evaluates key anatomical features including condylar process and tooth morphology (source needed).

Guideline-Based Recommendations

Diagnosis

  • Use DENTALE for standardized assessment of late dental adverse effects (source needed).

Management

  • Refer to specialized dental care when late effects exceed general dental management capabilities (source needed).

Monitoring & Follow-up

  • Conduct regular radiographic evaluations to assess dental development in survivors (source needed).

Risks

  • Late dental effects include agenesis, microdontia, enamel defects, and delayed eruption (source needed).

Patient & Prescribing Data

DENTALE aids in identifying the need for specialized dental interventions based on radiographic findings (source needed).

Clinical Best Practices

  • Utilize DENTALE for consistent evaluation across treatment modalities (source needed).
  • Engage multidisciplinary teams for complex dental cases (source needed).
  • Implement early referral strategies to mitigate future dental complications (source needed).

Related Resources & Content

Original Source(s)

DENTALE: a validated Dentofacial EvaluatioN Tool to standardize radiological Assessment of Late dental and maxillofacial adverse Effects following treatment for pediatric rhabdomyosarcoma

  • by Koen B. Krommenhoek, Reinier C. Hoogeveen, E. Foster-Thomas, Willem M. M. Fennis, Frédérique J. M. San Giorgi, Matthew Krasin, Mark N. Gaze, Olga Slater, Gillian A. Whitfield, Daniel J. Indelicato, Henry C. Mandeville, Shermaine Pan, Marianne C. Aznar, Johannes H. M. Merks, Alfred G. Becking, Marinka L. F. Hol

  • May 22, 2026

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