To analyze the differences in antibiotic resistance and biofilm-forming capacity of supragingival bacteria in patients with active dental caries compared to healthy controls.
Key Findings:
21% of Veillonella parvula isolates from patients with caries were susceptible to ampicillin compared to 73% from healthy patients.
79% of isolates from patients with caries were moderate biofilm producers, while 82% from healthy patients were non-biofilm producers.
Resistant bacteria in healthy patients were more frequently associated with stronger biofilm formation.
Moderate and strong biofilm-producing isolates showed higher antimicrobial resistance compared to non-biofilm producing isolates.
Beta-lactamase activity was confirmed in eight bacterial isolates, predominantly in Fusobacterium nucleatum.
Interpretation:
Remove this section.
Limitations:
Small sample size and uneven species representation across groups.
Potential intra-subject dependency due to multiple isolates from the same patient.
