The Fevers That Felled Napoleon’s Army
Genomic sequencing identifies pathogens behind one of military history’s greatest medical mysteries
Objective: To identify infectious diseases that may have contributed to the collapse of Napoleon's army during the 1812 retreat from Russia.
Key Findings: Genetic traces of paratyphoid fever and relapsing fever were identified in the soldiers. Four of the 13 individuals tested positive for S. enterica, and two for B. recurrentis. Historical accounts align with symptoms of paratyphoid infection, including diarrhea and fever. Interpretation: The findings suggest that multiple infections, exacerbated by harsh conditions, contributed to the high mortality rate among Napoleon's troops.
Limitations: The small sample size limits the ability to determine the full range of diseases affecting the soldiers. Clinical differentiation of overlapping symptoms would have been impossible at the time. Conclusion: The study underscores the importance of ancient DNA analysis in understanding historical disease outbreaks and their impact on military campaigns.