Long-Term Outcomes of Skill-Based Virtual Reality Therapy for High-Impact Chronic Pain: Findings from a Secondary Analysis of a Randomized Controlled Trial Over Two Years - Summary - DentalSpire

Long-Term Outcomes of Skill-Based Virtual Reality Therapy for High-Impact Chronic Pain: Findings from a Secondary Analysis of a Randomized Controlled Trial Over Two Years

  • By

  • Todd Maddox

  • Josh Sackman

  • Robert Bonakdar

  • Roselani Maddox

  • Beth D Darnall

  • April 23, 2026

  • 0 min

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Objective:

To examine the long-term effectiveness of skill-based VR therapy in patients with high-impact chronic pain (HICP) at 2 years posttreatment, highlighting its potential impact on clinical practice.

Key Findings:
  • Significant reductions in pain interference and pain intensity were observed in HICP patients at 2 years posttreatment, with p-values indicating statistical significance.
  • 70% of HICP patients were reclassified as LICP at end of treatment, with 67% maintaining this classification at 1 year posttreatment.
  • Greater reductions in sleep disturbance and physical disability were noted for HICP compared to LICP, with statistical significance.
Interpretation:

Skill-based VR therapy demonstrates durable efficacy in reducing pain and improving function in patients with HICP over a 2-year period, suggesting important implications for future research and clinical application.

Limitations:
  • No patient or public involvement in the analysis, which may limit the applicability of findings.
  • The study focused solely on the skill-based VR group, limiting broader applicability and potential biases.
Conclusion:

Skill-based VR therapy is a promising low-risk intervention for long-term management of high-impact chronic pain, leading to significant improvements in pain and daily functioning, warranting further studies to confirm long-term efficacy.

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