Financial toxicity as logistical and relational burden across the lifespan during autologous transplant preparation - Summary - DentalSpire

Financial toxicity as logistical and relational burden across the lifespan during autologous transplant preparation

  • By

  • Sean N. Halpin

  • April 30, 2026

  • 0 min

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Objective:

To examine how financial toxicity emerges during the preparation for autologous stem cell transplant (ASCT) in patients with multiple myeloma, focusing on its relational and logistical dimensions.

Key Findings:
  • Financial toxicity was rarely discussed explicitly but emerged through work disruption, travel demands, and caregiver burdens, reflecting a complex interplay of relational dynamics.
  • Patients often minimized financial concerns, prioritizing medical necessity over cost, framing financial hardship as an unavoidable consequence of treatment.
  • Caregivers absorbed substantial unpaid labor, exacerbating household financial strain and remaining largely invisible in clinical encounters.
Interpretation:

Financial toxicity is a dynamic and relational phenomenon that affects treatment readiness and decision-making, highlighting the need for proactive financial navigation in ASCT preparation, particularly in the context of caregiver roles.

Limitations:
  • The study relies on qualitative data, which may not be generalizable to all patient populations due to its context-specific nature.
  • Existing frameworks may not fully capture the complexities of financial toxicity across different age groups, particularly in relation to caregiving and functional independence.
Conclusion:

Understanding financial toxicity's manifestations during ASCT preparation can inform clinical practices and policies aimed at supporting patients and caregivers.

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