Proportion of Anal and Penile Squamous Cell Carcinoma Linked to HPV: A Study Conducted in Specialized Hospitals in Sri Lanka - Takeaways - DentalSpire

Proportion of Anal and Penile Squamous Cell Carcinoma Linked to HPV: A Study Conducted in Specialized Hospitals in Sri Lanka

  • By

  • W. D. J. K. Amarasena

  • Sampatha Goonewardena

  • K. D. B. M. Wijeratne

  • Vajirapani De Silva

  • Deepa Gamage

  • December 27, 2025

  • 0 min

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  • 1

    HPV is a major cause of anal and penile squamous cell carcinoma (SCC), with a significant global cancer burden linked to HPV infection.

  • 2

    In Sri Lanka, anal and penile cancers are rising among men, particularly among those with high-risk sexual behaviors, including MSM.

  • 3

    The study aimed to determine the proportion of anal and penile SCC attributed to HPV and the population attributable risk percentage in Sri Lanka.

  • 4

    HPV vaccination strategies should be extended to high-risk males, especially MSM, to prevent HPV-related cancers and protect women's health.

  • 5

    The study utilized a case-control design, recruiting adult males diagnosed with anal or penile SCC from specialized hospitals in Gampaha District.

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