Reactive lymphoid hyperplasia of the appendix in children: a descriptive analysis of accompanying neural and stromal features - Takeaways - DentalSpire

Reactive lymphoid hyperplasia of the appendix in children: a descriptive analysis of accompanying neural and stromal features

  • By

  • Neslihan Gulcin

  • Ilkay Tosun

  • Ceyhan Sahin

  • May 1, 2026

  • 0 min

Share

  • 1

    Reactive lymphoid hyperplasia (RLH) is commonly found in pediatric appendectomy specimens, often mistaken for acute appendicitis.

  • 2

    The study identified 100 cases of RLH among 468 appendectomies, with a mean patient age of 11.34 years and a predominance of males.

  • 3

    Neural and stromal alterations, including S-100 positive nerve elements and fibrosis, were frequently observed in RLH cases.

  • 4

    RLH should not be considered a completely normal appendix, as it may present with nonspecific reactive changes.

  • 5

    Further research is needed to clarify the clinical significance of neural and stromal alterations associated with RLH.

Original Source(s)

Reactive lymphoid hyperplasia of the appendix in children: a descriptive analysis of accompanying neural and stromal features

  • by Neslihan Gulcin, Ilkay Tosun, Ceyhan Sahin

  • May 1, 2026

Related Content

Grill Brush Bristle Injuries Continue to Rise

Most patients were treated and released, with the oropharynx the most common injury site

Obituary: Jesús Saldaña García

Silencing TMED2 suppresses cell growth and tumor progression in diffuse large B-cell lymphoma via inducing G0/G1 cell cycle arrest