DENTALE: a validated Dentofacial EvaluatioN Tool to standardize radiological Assessment of Late dental and maxillofacial adverse Effects following treatment for pediatric rhabdomyosarcoma - Takeaways - DentalSpire

DENTALE: a validated Dentofacial EvaluatioN Tool to standardize radiological Assessment of Late dental and maxillofacial adverse Effects following treatment for pediatric rhabdomyosarcoma

  • By

  • Koen B. Krommenhoek

  • Reinier C. Hoogeveen

  • E. Foster-Thomas

  • Willem M. M. Fennis

  • Frédérique J. M. San Giorgi

  • Matthew Krasin

  • Mark N. Gaze

  • Olga Slater

  • Gillian A. Whitfield

  • Daniel J. Indelicato

  • Henry C. Mandeville

  • Shermaine Pan

  • Marianne C. Aznar

  • Johannes H. M. Merks

  • Alfred G. Becking

  • Marinka L. F. Hol

  • May 22, 2026

  • 0 min

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  • 1

    DENTALE is a newly developed radiographic evaluation tool for assessing late dental adverse effects in pediatric rhabdomyosarcoma survivors.

  • 2

    The tool was validated through systematic assessment of orthopantomograms (OPGs) from a cohort of childhood cancer survivors.

  • 3

    Interobserver reliability for DENTALE showed good to excellent agreement, with ICC values ranging from 0.857 to 0.939.

  • 4

    DENTALE achieved 100% sensitivity and 90% specificity for referral decisions to specialized dental care using a threshold score of 16.

  • 5

    The tool aims to standardize the assessment of late dental effects, facilitating comparisons across treatments and improving patient management.

Original Source(s)

DENTALE: a validated Dentofacial EvaluatioN Tool to standardize radiological Assessment of Late dental and maxillofacial adverse Effects following treatment for pediatric rhabdomyosarcoma

  • by Koen B. Krommenhoek, Reinier C. Hoogeveen, E. Foster-Thomas, Willem M. M. Fennis, Frédérique J. M. San Giorgi, Matthew Krasin, Mark N. Gaze, Olga Slater, Gillian A. Whitfield, Daniel J. Indelicato, Henry C. Mandeville, Shermaine Pan, Marianne C. Aznar, Johannes H. M. Merks, Alfred G. Becking, Marinka L. F. Hol

  • May 22, 2026

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