Epidemiological Trends of Hand, Foot, and Mouth Disease Across Three Distinct Periods in Jiangxi Province, China: A Retrospective Analysis from 2009 to 2022 - Takeaways - DentalSpire

Epidemiological Trends of Hand, Foot, and Mouth Disease Across Three Distinct Periods in Jiangxi Province, China: A Retrospective Analysis from 2009 to 2022

  • By

  • Jia Hu

  • Lihui Yu

  • Zijing Peng

  • Huanhong Pan

  • Yuan Jin

  • Zhili Zeng

  • Guanghui Xia

  • Yuan Wang

  • Zifen Li

  • Jianxiong Li

  • Yong Shi

  • Dajin Xiao

  • Haifeng Pan

  • Xiaoqing Liu

  • Tianchen Zhang

  • January 29, 2026

  • 0 min

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  • 1

    Hand, foot, and mouth disease (HFMD) primarily affects children under 5 years and can lead to severe complications, including fatalities.

  • 2

    The inactivated EV-A71 vaccine, introduced in 2016, has shown 97% effectiveness against EV-A71 associated HFMD with mild adverse reactions.

  • 3

    Jiangxi Province in China has experienced recurrent HFMD outbreaks, necessitating an evaluation of vaccination and non-pharmacological interventions (NPI) effects.

  • 4

    The study analyzed HFMD surveillance data from 2009 to 2022, employing statistical models to assess the impact of vaccination and NPI on disease trends.

  • 5

    Findings highlight the need for integrated public health strategies to enhance HFMD prevention, considering vaccination limitations and NPI effectiveness.

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