Case Report: When inotropy backfires—dobutamine-associated eosinophilic myocarditis - Takeaways - DentalSpire

Case Report: When inotropy backfires—dobutamine-associated eosinophilic myocarditis

  • By

  • Abdullah Aljudaibi

  • Kristi Dutta

  • Sahitya Allam

  • Jose-Alejandro Almario

  • Lo Tamburro

  • Lynn Dees

  • Erik Sorensen

  • Bartley P. Griffith

  • Gautam Ramani

  • Manjula Ananthram

  • April 30, 2026

  • 0 min

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  • 1

    Eosinophilic myocarditis can be triggered by drug hypersensitivity, as demonstrated in a case involving dobutamine.

  • 2

    A 55-year-old man with dilated non-ischemic cardiomyopathy developed cardiogenic shock requiring left ventricular assist device implantation.

  • 3

    Left ventricular biopsy revealed eosinophilic infiltration, confirming the diagnosis of dobutamine-associated eosinophilic myocarditis.

  • 4

    Discontinuation of dobutamine and initiation of corticosteroids led to improved ventricular function and hemodynamics.

  • 5

    Clinicians should consider drug-induced eosinophilic myocarditis in patients with refractory cardiogenic shock receiving dobutamine.

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